Keratoconus is an eye condition that may not be as well-known as nearsightedness or farsightedness, but it significantly affects the lives of those it touches. This progressive eye disease causes the cornea, which is normally round, to thin and bulge outward into a cone-like shape. This deformation distorts the vision, as the light entering the eye cannot be focused correctly. In this detailed guide, we will explore the causes of keratoconus, its symptoms, and the latest treatment options available, providing valuable information for patients and caregivers seeking a deeper understanding of this condition.

What is Keratoconus?

Keratoconus is a progressive eye disorder that generally begins during a person’s teenage years and can continue to worsen until around age 40. The condition is characterized by a gradual thinning and bulging of the cornea, the clear outer lens of the eye. This distortion leads to progressive nearsightedness and irregular astigmatism, which can cause significant visual impairment.

Causes of Keratoconus

The exact cause of keratoconus is not fully understood, but it is believed to involve a combination of genetic and environmental factors. Here are some of the potential causes:

  • Genetic Factors: There is a hereditary component, as approximately 10% of people with keratoconus have a family member with the condition. Specific genes associated with keratoconus have been identified, which may affect the structure and stability of corneal tissue.
  • Oxidative Stress: Some researchers believe that oxidative stress can play a role in degrading the cornea. The cornea absorbs a significant amount of ultraviolet light, which can increase oxidative damage and weaken the corneal fibers, especially if antioxidant defenses are compromised.
  • Eye Rubbing: Chronic eye rubbing has been shown to correlate strongly with the progression of keratoconus. It is thought that the mechanical stress of rubbing the eyes can contribute to the weakening of the corneal structure.
  • Hormonal Changes: Hormonal changes, particularly during puberty, may also influence the progression of keratoconus. This could help explain why the condition often begins in the teenage years.

Symptoms of Keratoconus

The symptoms of keratoconus can vary as the disease progresses, but typically include:

  • Blurring and Distortion of Vision: As the cornea becomes more irregular in shape, it causes progressive blurring and distortion of vision.
  • Increased Light Sensitivity: Patients may experience significant glare and light sensitivity, which can be particularly problematic during night driving.
  • Frequent Changes in Eyeglass Prescription: A hallmark of keratoconus is the frequent need to change one’s eyeglass prescription as the shape of the cornea changes.
  • Seeing Halos Around Lights: The irregular shape of the cornea can cause light to scatter rather than focus precisely on the retina, leading to visual halos around bright lights.

Diagnosing Keratoconus

Diagnosis of keratoconus involves a thorough eye exam, including:

  • Corneal Topography: The most definitive tool for diagnosing keratoconus is corneal topography, which creates a detailed map of the curvature of the cornea and shows distortions and thinning characteristic of the condition.
  • Visual Acuity Test: A standard eye chart test helps assess the impact of keratoconus on visual acuity.
  • Slit-Lamp Examination: This examination allows the doctor to see the structures at the front of the eye under magnification, which can help detect early signs of keratoconus.

Treatment Options for Keratoconus

While there is no cure for keratoconus, several treatments can help manage symptoms and slow or even halt its progression:

  • Eyeglasses or Soft Contact Lenses: In early stages, the vision issues caused by keratoconus can often be corrected with glasses or soft contact lenses.
  • Rigid Gas Permeable Contact Lenses: As the condition progresses, rigid gas permeable contact lenses may be necessary to correct vision more effectively.
  • Corneal Crosslinking (CXL): This relatively new treatment helps strengthen corneal tissue to halt the progression of keratoconus. It involves applying vitamin B2 (riboflavin) to the cornea and then activating it with UV light.
  • Corneal Transplant: In severe cases, when vision can no longer be corrected with contact lenses, a corneal transplant may be necessary.

Living with Keratoconus

Living with keratoconus requires regular monitoring and treatment to ensure the best possible vision and quality of life. Patients need to have regular check-ups with an eye care professional who is experienced in treating keratoconus. Avoiding eye rubbing and wearing UV-protective sunglasses to limit UV exposure can also help manage the condition.

Keratoconus can be a challenging and frustrating condition, with a significant impact on a person’s ability to perform daily activities. However, with proper management and the use of advanced treatment options, many people with keratoconus can lead full and productive lives. Understanding the causes, recognizing the symptoms, and seeking timely treatment are crucial steps in dealing with this complex eye disorder effectively.